Detection of bond formations by DNA-programmed chemical reactions and PCR amplification.
نویسندگان
چکیده
A system capable of performing both DNA-templated chemical reactions and detection of bond formations is reported. Photocleavable DNA templates direct reactions. Products from bond-forming events re-ligate original templates, amplifiable by PCR, therefore distinguishing bond formation from background. This system provides a novel approach for discovering potential new chemical reactions.
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ورودعنوان ژورنال:
- Chemical communications
دوره 48 76 شماره
صفحات -
تاریخ انتشار 2012